C-Telopeptide, Beta-Cross-Linked, Serum - ARUP Laboratories

Ordering Recommendation

Recommendations when to order or not order the test. May include related or preferred tests.

Preferred test to measure bone resorption and monitor response to antiresorptive therapy (eg, bisphosphonates, hormone replacement therapy) in postmenopausal women and individuals with osteoporosis.

New York DOH Approval Status

Indicates whether a test has been approved by the New York State Department of Health.

This test is New York state approved.

Specimen Required

Patient PreparationInstructions patient must follow before/during specimen collection.

Fasting specimen preferred.

CollectSpecimen type to collect. May include collection media, tubes, kits, etc.

Serum separator tube, lavender (K2 EDTA or K3 EDTA), pink (K2 EDTA). A morning specimen is preferred.

Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.

Allow serum separator tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.

Frozen

Unacceptable ConditionsCommon conditions under which a specimen will be rejected.

Hemolyzed specimens. Green lithium heparin plasma

StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.

After separation from cells: Ambient: 24 hours; Refrigerated: 48 hours; Frozen: 3 months

Methodology

Process(es) used to perform the test.

Quantitative Electrochemiluminescent Immunoassay

Performed

Days of the week the test is performed.

Sun-Sat

Reported

Expected turnaround time for a result, beginning when ARUP has received the specimen.

Within 24 hours

Reference Interval

Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.

Age	Female	Male
6 months-6 years	500-1800 pg/mL	500-1700 pg/mL
7-9 years	566-1690 pg/mL	522-1682 pg/mL
10-12 years	503-2077 pg/mL	553-2071 pg/mL
13-15 years	160-1590 pg/mL	485-2468 pg/mL
16-17 years	167-933 pg/mL	276-1546 pg/mL
18-29 years		238-1019 pg/mL
30-39 years		225-936 pg/mL
40-49 years		182-801 pg/mL
50-59 years		161-737 pg/mL
60-69 years		132-752 pg/mL
70 years or greater		118-776 pg/mL
Premenopausal	136-689 pg/mL
Postmenopausal	177-1015 pg/mL

Interpretive Data

May include disease information, patient result explanation, recommendations, or details of testing.

Compliance Category

FDA

Note

Additional information related to the test.

Hotline History

N/A

CPT Codes

The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually.
CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ.
CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.

82523

Components

Components of test

Component Test Code*	Component Chart Name	LOINC
0070415	C-Telopeptide, Beta-Cross-Linked, Serum	41171-0

* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Other names that describe the test. Synonyms.

• B-Cross Laps
• Collagen Type I-C
• bone resorption marker
• Beta-CTx
• Collagen Type I-C Telopeptide
• B-CTx
• Beta-Cross Laps
• CTx
• Collagen C Telopeptide
• C-Telopeptide
• C-terminal collagen crosslinks
• Carboxy terminal collagen crosslinks

C-Telopeptide, Beta-Cross-Linked, Serum