Dermalogica Pro-Collagen Banking Serum Versus Prequel Multi-Quench Plumping Hydration Serum

Dermalogica Pro-Collagen Banking Serum Versus Prequel Multi-Quench Plumping Hydration Serum

This anti-aging serum is formulated around Trehalose and Carnosine to soften the look of wrinkles and strengthen the skin barrier.

This hydrating serum is formulated around Polyglutamic Acid and Ectoin to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Pentylene Glycol

Coco-Caprylate/Caprate

Glycerin

Propanediol

Simmondsia Chinensis Seed Oil

Trehalose

Oryza Sativa Bran Water

Butylene Glycol

Ethoxydiglycol

Triheptanoin

Arginine PCA

Diglycerin

Dipotassium Glycyrrhizate

Sodium Hyaluronate

Collagen Amino Acids

Glycine Soja Oil

Helianthus Annuus Seed Oil

Citrus Aurantium Dulcis Peel Oil

Citrus Aurantium Bergamia Fruit Oil

Citrus Paradisi Peel Oil

Rosmarinus Officinalis Leaf Extract

Cupressus Sempervirens Leaf/Nut/Stem Oil

Santalum Album Oil

Citrus Limon Peel Oil

Rosa Damascena Flower Oil

Jasminum Sambac Flower Extract

Hydrolyzed Jojoba Esters

Oryza Sativa Bran Extract

Aloe Barbadensis Leaf Extract

Tephrosia Purpurea Seed Extract

Helianthus Annuus Extract

Juniperus Virginiana Oil

Tagetes Minuta Flower Oil

Rosmarinus Officinalis Leaf Oil

Cistus Ladaniferus Leaf/Stem Extract

Hydrolyzed Rice Protein

Tocopheryl Acetate

Tocopherol

Phospholipids

Carnosine

Glyceryl Stearate Citrate

Caprylyl Glycol

Polyglutamic Acid

Glycolipids

Glycine Soja Sterols

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Glyceryl Caprylate

Sclerotium Gum

Polyquaternium-80

Didecyldimonium Chloride

Dianthus Caryophyllus Flower Extract

Xanthan Gum

Methylpropanediol

Cetearyl Alcohol

PEG-40 Hydrogenated Castor Oil

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Phytic Acid

Polysorbate 20

Tetrasodium Glutamate Diacetate

Citric Acid

Sodium Hydroxide

Sodium Polyacryloyldimethyl Taurate

Sodium Benzoate

Potassium Sorbate

Limonene

Linalool

Water, Pentylene Glycol, Coco-Caprylate/Caprate, Glycerin, Propanediol, Simmondsia Chinensis Seed Oil, Trehalose, Oryza Sativa Bran Water, Butylene Glycol, Ethoxydiglycol, Triheptanoin, Arginine PCA, Diglycerin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Collagen Amino Acids, Glycine Soja Oil, Helianthus Annuus Seed Oil, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantium Bergamia Fruit Oil, Citrus Paradisi Peel Oil, Rosmarinus Officinalis Leaf Extract, Cupressus Sempervirens Leaf/Nut/Stem Oil, Santalum Album Oil, Citrus Limon Peel Oil, Rosa Damascena Flower Oil, Jasminum Sambac Flower Extract, Hydrolyzed Jojoba Esters, Oryza Sativa Bran Extract, Aloe Barbadensis Leaf Extract, Tephrosia Purpurea Seed Extract, Helianthus Annuus Extract, Juniperus Virginiana Oil, Tagetes Minuta Flower Oil, Rosmarinus Officinalis Leaf Oil, Cistus Ladaniferus Leaf/Stem Extract, Hydrolyzed Rice Protein, Tocopheryl Acetate, Tocopherol, Phospholipids, Carnosine, Glyceryl Stearate Citrate, Caprylyl Glycol, Polyglutamic Acid, Glycolipids, Glycine Soja Sterols, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Caprylate, Sclerotium Gum, Polyquaternium-80, Didecyldimonium Chloride, Dianthus Caryophyllus Flower Extract, Xanthan Gum, Methylpropanediol, Cetearyl Alcohol, PEG-40 Hydrogenated Castor Oil, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Phytic Acid, Polysorbate 20, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Hydroxide, Sodium Polyacryloyldimethyl Taurate, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool

1,2-Hexanediol

Ectoin

Hibiscus Esculentus Fruit Extract

Erythritol

Phenoxyethanol

Carbomer

Ethylhexylglycerin

Water, Glycerin, Butylene Glycol, Polyglutamic Acid, 1,2-Hexanediol, Ectoin, Hibiscus Esculentus Fruit Extract, Erythritol, Phenoxyethanol, Propanediol, Xanthan Gum, Caprylyl Glycol, Carbomer, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Citric Acid, Sodium Hydroxide

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Polyglutamic Acid is made up many glutamic acids chained together. It is created from bacterial fermentation.

This ingredient is an effective skin hydrator and may help speed up wound healing. As a humectant, it draws and holds water to the skin. This ingredient is often compared to hyaluronic acid or glycerin. Similarly to hyaluronic acid, it can vary in molecular weights. This means polyglutamic acid is capable of bringing hydration to lower levels of the skin.

Fun fact: Polyglutamic Acid is found in the Japanese food, natto. It is also being used in cancer treatment studies.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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