Dr. Althea Vitamin C Boosting Serum Versus MediCube Deep Collagen Vita Multi Serum Stick

Dr. Althea Vitamin C Boosting Serum Versus MediCube Deep Collagen Vita Multi Serum Stick

This brightening serum is formulated around Niacinamide and Tranexamic Acid to brighten dull-looking skin and fade the look of dark spots.

This anti-aging serum is formulated around Ascorbic Acid and Copper Tripeptide-1 to soften the look of wrinkles and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Hippophae Rhamnoides Water

Centella Asiatica Leaf Water

Niacinamide

Butylene Glycol

1,2-Hexanediol

Dipropylene Glycol

Water

Methyl Gluceth-20

Methylpropanediol

Betaine

Tranexamic Acid

Glycerin

Pentylene Glycol

Propanediol

Hydroxyethyl Urea

Laminaria Japonica Extract

Eclipta Prostrata Leaf Extract

Ficus Carica Fruit Extract

Centella Asiatica Extract

Hydrogenated Lecithin

Sodium Hyaluronate

Carbomer

3-O-Ethyl Ascorbic Acid

C12-14 Pareth-12

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Xanthan Gum

Tromethamine

Panthenol

Ethylhexylglycerin

Adenosine

Disodium EDTA

Fructooligosaccharides

Beta-Glucan

Ascorbic Acid

Hydrolyzed Hyaluronic Acid

Ceramide NP

Alpha-Arbutin

Tocopherol

Bifida Ferment Lysate

Bisabolol

Ubiquinone

Hydroxydecyl Ubiquinone

Sodium Acetylated Hyaluronate

Hippophae Rhamnoides Water, Centella Asiatica Leaf Water, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Dipropylene Glycol, Water, Methyl Gluceth-20, Methylpropanediol, Betaine, Tranexamic Acid, Glycerin, Pentylene Glycol, Propanediol, Hydroxyethyl Urea, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Ficus Carica Fruit Extract, Centella Asiatica Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Carbomer, 3-O-Ethyl Ascorbic Acid, C12-14 Pareth-12, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Xanthan Gum, Tromethamine, Panthenol, Ethylhexylglycerin, Adenosine, Disodium EDTA, Fructooligosaccharides, Beta-Glucan, Ascorbic Acid, Hydrolyzed Hyaluronic Acid, Ceramide NP, Alpha-Arbutin, Tocopherol, Bifida Ferment Lysate, Bisabolol, Ubiquinone, Hydroxydecyl Ubiquinone, Sodium Acetylated Hyaluronate

Helianthus Annuus Seed Oil

Vegetable Oil

Ceresin

Polyglyceryl-2 Triisostearate

Diisostearyl Malate

Cetyl Ethylhexanoate

Hexyldecyl Ethylhexanoate

Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate

Beeswax

Copernicia Cerifera Wax

Shorea Robusta Seed Butter

Sucrose Tetrastearate Triacetate

Caprylyl Glycol

Eclipta Prostrata Extract

Ferulic Acid

Tocopheryl Acetate

Glycyrrhiza Glabra Root Extract

Moringa Oleifera Seed Oil

Glycine Soja Peptide

Sorbitan Laurate

Soluble Collagen

Hydrolyzed Collagen

Hydroxyethylcellulose

Acetyl Dipeptide-1 Cetyl Ester

Acetyl Hexapeptide-1

Acetyl Hexapeptide-8

Copper Tripeptide-1

Palmitoyl Tripeptide-5

Acetyl Octapeptide-3

Palmitoyl Pentapeptide-4

Atelocollagen

Oligopeptide-1

Oligopeptide-2

Helianthus Annuus Seed Oil, Vegetable Oil, Ascorbic Acid, Ceresin, Polyglyceryl-2 Triisostearate, Diisostearyl Malate, Cetyl Ethylhexanoate, Hexyldecyl Ethylhexanoate, Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate, Beeswax, Copernicia Cerifera Wax, Shorea Robusta Seed Butter, Sucrose Tetrastearate Triacetate, Dipropylene Glycol, Tocopherol, Caprylyl Glycol, Eclipta Prostrata Extract, Ethylhexylglycerin, Eclipta Prostrata Leaf Extract, Ferulic Acid, Tocopheryl Acetate, Glycyrrhiza Glabra Root Extract, Adenosine, Moringa Oleifera Seed Oil, Water, Butylene Glycol, Propanediol, 1,2-Hexanediol, Glycerin, Glycine Soja Peptide, Sodium Hyaluronate, Sorbitan Laurate, Soluble Collagen, Hydrolyzed Collagen, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-5, Acetyl Octapeptide-3, Palmitoyl Pentapeptide-4, Atelocollagen, Oligopeptide-1, Oligopeptide-2

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.

Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:

Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.

One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.

While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.

The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.

Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.

Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Eclipta Prostrata Leaf Extract comes from the false daisy plant. False daisy contains antioxidant compounds such as flavonoids.

One study found false daisy to absorb UVA and UVB radiation. However, this should not replace your sunscreen.

False daisy is used in both traditional medicines and foods throughout Southeast Asia and India.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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