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Dr. Dennis Gross Skincare C+ Collagen Brighten & Firm Vitamin C Serum Versus Shiseido Benefiance Wrinkle Smoothing Contour Serum

Dr. Dennis Gross Skincare C+ Collagen Brighten & Firm Vitamin C Serum Versus Shiseido Benefiance Wrinkle Smoothing Contour Serum This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Niacinamide to brighten dull-looking skin and soften the lo

Dr. Dennis Gross Skincare C+ Collagen Brighten & Firm Vitamin C Serum Versus Shiseido Benefiance Wrinkle Smoothing Contour Serum

This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Niacinamide to brighten dull-looking skin and soften the look of wrinkles.

This anti-aging serum is formulated around Retinyl Acetate and Caffeine to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

3-O-Ethyl Ascorbic Acid

Niacinamide

Glycereth-7 Triacetate

Lactic Acid

Sd Alcohol 40-B

Hydroxyethylcellulose

Dimethyl Isosorbide

Ascorbic Acid

Collagen Amino Acids

Superoxide Dismutase

Glycine

Carnitine Hcl

Ubiquinone

Hexylresorcinol

Emblica Officinalis Fruit Extract

Hydrolyzed Soy Protein

Tetrahexyldecyl Ascorbate

Isoquercetin

Mandelic Acid

Pueraria Lobata Root Extract

Curcuma Longa Root Extract

Phytic Acid

Citric Acid

Tetrasodium EDTA

Sodium Citrate

Butylene Glycol

Xanthan Gum

Polysorbate 20

T-Butyl Alcohol

Sodium Hydroxide

Polysorbate 80

Denatonium Benzoate

Benzyl Alcohol

Phenoxyethanol

Sodium Benzoate

Potassium Sorbate

Water, Glycerin, 3-O-Ethyl Ascorbic Acid, Niacinamide, Glycereth-7 Triacetate, Lactic Acid, Sd Alcohol 40-B, Hydroxyethylcellulose, Dimethyl Isosorbide, Ascorbic Acid, Collagen Amino Acids, Superoxide Dismutase, Glycine, Carnitine Hcl, Ubiquinone, Hexylresorcinol, Emblica Officinalis Fruit Extract, Hydrolyzed Soy Protein, Tetrahexyldecyl Ascorbate, Isoquercetin, Mandelic Acid, Pueraria Lobata Root Extract, Curcuma Longa Root Extract, Phytic Acid, Citric Acid, Tetrasodium EDTA, Sodium Citrate, Butylene Glycol, Xanthan Gum, Polysorbate 20, T-Butyl Alcohol, Sodium Hydroxide, Polysorbate 80, Denatonium Benzoate, Benzyl Alcohol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Pentaerythrityl Tetraethylhexanoate

Dimethicone

Dipropylene Glycol

Behenyl Alcohol

Silica

PEG-400

Batyl Alcohol

Methylparaben

Carbomer

Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer

Trisodium EDTA

Tocopheryl Acetate

Retinyl Acetate

Alcohol

Helianthus Annuus Seed Oil

BHT

Polyquaternium-51

Parfum

Potassium Hydroxide

Caffeine

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

PPG-3 Dipivalate

Rosa Canina Fruit Oil

CI 77492

Tocopherol

Sapindus Mukorossi Peel Extract

Linalool

Limonene

Sodium Metabisulfite

Triisostearin

Uncaria Gambir Extract

Citronellol

Angelica Keiskei Leaf/Stem Extract

Trimethylolpropane Triethylhexanoate

Geraniol

Cellulose

Camellia Sinensis Leaf Extract

Sodium Acetylated Hyaluronate

Hydroxyproline

Ziziphus Jujuba Fruit Extract

Chlorella Vulgaris Extract

Methicone

Tetradecene

Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract

Curcuma Longa Rhizome Extract

Saccharina Angustata/Undaria Pinnatifida Extract

Panax Ginseng Root Extract

Ascorbyl Dipalmitate

Water, Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Dimethicone, Glycerin, Dipropylene Glycol, Sd Alcohol 40-B, Behenyl Alcohol, Silica, PEG-400, Batyl Alcohol, Phenoxyethanol, Methylparaben, Carbomer, Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer, Trisodium EDTA, Tocopheryl Acetate, Retinyl Acetate, Alcohol, Helianthus Annuus Seed Oil, BHT, Polyquaternium-51, Parfum, Potassium Hydroxide, Caffeine, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, PPG-3 Dipivalate, Rosa Canina Fruit Oil, CI 77492, Tocopherol, Sapindus Mukorossi Peel Extract, Linalool, Limonene, Sodium Metabisulfite, Triisostearin, Uncaria Gambir Extract, Citronellol, Angelica Keiskei Leaf/Stem Extract, Trimethylolpropane Triethylhexanoate, Geraniol, Cellulose, Camellia Sinensis Leaf Extract, Sodium Acetylated Hyaluronate, Hydroxyproline, Ziziphus Jujuba Fruit Extract, Chlorella Vulgaris Extract, Methicone, Tetradecene, Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract, Curcuma Longa Rhizome Extract, Saccharina Angustata/Undaria Pinnatifida Extract, Panax Ginseng Root Extract, Ascorbyl Dipalmitate

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

SD Alcohol 40-B is created by denaturing ethanol with tert-Butyl alcohol and denatonium benzoate. It is a solvent and astringent.

The 'SD' stands for 'specially denatured'. Denatured alcohol means the structure has been altered.

The 40-B is given by the U.S. Bureau of Alcohol, Tobacco, and Firearms. This is in accordance to the method of how the alcohol was denatured.

This ingredient is a solvent alcohol.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

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REFERENCE CARDS

Ingredients, lists & structured values

INGREDIENT LIST

Ingredients Explained

  • These ingredients are found in both products.
  • Ingredients higher up in an ingredient list are typically present in a larger amount.
  • Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  • Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  • Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  • Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  • Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  • It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  • Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  • A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  • Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  • Topically, glycerin does several things at once:
  • Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  • Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  • This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  • Just know very high concentrations (>40%) can feel tacky in low humidity.
  • Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  • Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
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PROVISION SHELF

Products & side-by-side records