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Nutrition guide

Dr. Dennis Gross Skincare C+ Collagen Deep Cream Versus Dr. Dennis Gross Skincare B³Adaptive SuperFoods™ Stress Repair Face Cream

Dr. Dennis Gross Skincare C+ Collagen Deep Cream Versus Dr. Dennis Gross Skincare B³Adaptive SuperFoods™ Stress Repair Face Cream This brightening treatment is formulated around 3-O-Ethyl Ascorbic Acid and Niacinamide to brighten dull-looking skin and soften t

Dr. Dennis Gross Skincare C+ Collagen Deep Cream Versus Dr. Dennis Gross Skincare B³Adaptive SuperFoods™ Stress Repair Face Cream

This brightening treatment is formulated around 3-O-Ethyl Ascorbic Acid and Niacinamide to brighten dull-looking skin and soften the look of wrinkles.

This barrier-repair moisturizer is formulated around Prunus Amygdalus Dulcis Oil and Niacinamide to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Camellia Japonica Seed Oil

Oryza Sativa Bran Oil

Dimethicone

Sucrose

Pentylene Glycol

Helianthus Annuus Seed Oil

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

3-O-Ethyl Ascorbic Acid

Collagen Amino Acids

Niacinamide

Carnitine Hcl

Hydroxyproline

Glycine

Carnitine

Squalane

Dipotassium Glycyrrhizate

Tocopherol

Saccharide Isomerate

Acetyl Hexapeptide-8

Superoxide Dismutase

Leuconostoc/Radish Root Ferment Filtrate

Ubiquinone

Aloe Barbadensis Leaf Juice

Lactobacillus Ferment

Undaria Pinnatifida Extract

Glycolic Acid

Lecithin

Biotin

Maltodextrin

Caprylyl Glycol

1,2-Hexanediol

Carbomer

Hydroxyethylcellulose

Ammonium Hydroxide

Polysorbate 60

Potassium Hydroxide

Sodium Phytate

Sodium Citrate

Citric Acid

Camellia Sinensis Leaf Extract

Cucumis Sativus Fruit Extract

Elettaria Cardamomum Seed Extract

Citrus Aurantium Amara Flower Extract

Cupressus Sempervirens Leaf/Stem Extract

Fucus Vesiculosus Extract

Pyrus Malus Fruit Extract

Rubus Idaeus Fruit Extract

Cananga Odorata Flower Extract

Coffea Arabica Seed Extract

Rose Extract

Cucumis Melo Fruit Extract

Jasminum Officinale Flower Extract

Rosmarinus Officinalis Leaf Extract

Citrus Aurantium Bergamia Fruit Extract

Salvia Officinalis Leaf Extract

Lavandula Angustifolia Flower/Leaf/Stem Extract

Santalum Album Wood Extract

Triethyl Citrate

Phenoxyethanol

Potassium Sorbate

Water, Glycerin, Butylene Glycol, Camellia Japonica Seed Oil, Oryza Sativa Bran Oil, Dimethicone, Sucrose, Pentylene Glycol, Helianthus Annuus Seed Oil, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, 3-O-Ethyl Ascorbic Acid, Collagen Amino Acids, Niacinamide, Carnitine Hcl, Hydroxyproline, Glycine, Carnitine, Squalane, Dipotassium Glycyrrhizate, Tocopherol, Saccharide Isomerate, Acetyl Hexapeptide-8, Superoxide Dismutase, Leuconostoc/Radish Root Ferment Filtrate, Ubiquinone, Aloe Barbadensis Leaf Juice, Lactobacillus Ferment, Undaria Pinnatifida Extract, Glycolic Acid, Lecithin, Biotin, Maltodextrin, Caprylyl Glycol, 1,2-Hexanediol, Carbomer, Hydroxyethylcellulose, Ammonium Hydroxide, Polysorbate 60, Potassium Hydroxide, Sodium Phytate, Sodium Citrate, Citric Acid, Camellia Sinensis Leaf Extract, Cucumis Sativus Fruit Extract, Elettaria Cardamomum Seed Extract, Citrus Aurantium Amara Flower Extract, Cupressus Sempervirens Leaf/Stem Extract, Fucus Vesiculosus Extract, Pyrus Malus Fruit Extract, Rubus Idaeus Fruit Extract, Cananga Odorata Flower Extract, Coffea Arabica Seed Extract, Rose Extract, Cucumis Melo Fruit Extract, Jasminum Officinale Flower Extract, Rosmarinus Officinalis Leaf Extract, Citrus Aurantium Bergamia Fruit Extract, Salvia Officinalis Leaf Extract, Lavandula Angustifolia Flower/Leaf/Stem Extract, Santalum Album Wood Extract, Triethyl Citrate, Phenoxyethanol, Potassium Sorbate

Prunus Amygdalus Dulcis Oil

Ethylhexyl Palmitate

Propanediol

Persea Gratissima Fruit Extract

Actinidia Chinensis Fruit Extract

Cordyceps Sinensis Extract

Terminalia Ferdinandiana Fruit Extract

Lycium Barbarum Fruit Extract

Lepidium Meyenii Root Extract

Phyllanthus Emblica Fruit Extract

Euterpe Oleracea Sterols

Curcuma Longa Root Oil

Pleiogynium Timoriense Fruit Extract

Grifola Frondosa Extract

Theobroma Cacao Extract

Podocarpus Elatus Fruit Extract

Inonotus Obliquus Extract

Perilla Frutescens Extract

Withania Somnifera Root Extract

Asparagus Racemosus Root Extract

Rhodiola Rosea Root Extract

Hydrolyzed Sodium Hyaluronate

Zingiber Officinale Root Oil

Cymbopogon Schoenanthus Oil

Sesamum Indicum Seed Oil

Linoleic Acid

Linolenic Acid

Oleic Acid

Lysolecithin

Hydrogenated Phosphatidylcholine

Beta-Sitosterol

Phospholipids

Sphingolipids

Colloidal Oatmeal

Ceramide Ng

Adenosine

Sodium PCA

Ethylhexylglycerin

Panthenol

Allantoin

Lactic Acid

Phytic Acid

Cyclodextrin

Sodium Hydroxide

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polyacrylate-13

Polyisobutene

Polysorbate 20

Sorbitan Isostearate

Sodium Benzoate

Water, Prunus Amygdalus Dulcis Oil, Ethylhexyl Palmitate, Propanediol, Niacinamide, Glycerin, Squalane, Persea Gratissima Fruit Extract, Actinidia Chinensis Fruit Extract, Cordyceps Sinensis Extract, Terminalia Ferdinandiana Fruit Extract, Lycium Barbarum Fruit Extract, Lepidium Meyenii Root Extract, Phyllanthus Emblica Fruit Extract, Euterpe Oleracea Sterols, Curcuma Longa Root Oil, Pleiogynium Timoriense Fruit Extract, Grifola Frondosa Extract, Theobroma Cacao Extract, Podocarpus Elatus Fruit Extract, Inonotus Obliquus Extract, Perilla Frutescens Extract, Withania Somnifera Root Extract, Asparagus Racemosus Root Extract, Rhodiola Rosea Root Extract, Hydrolyzed Sodium Hyaluronate, Helianthus Annuus Seed Oil, Zingiber Officinale Root Oil, Cymbopogon Schoenanthus Oil, Sesamum Indicum Seed Oil, Linoleic Acid, Linolenic Acid, Oleic Acid, Lecithin, Lysolecithin, Hydrogenated Phosphatidylcholine, Beta-Sitosterol, Phospholipids, Sphingolipids, Colloidal Oatmeal, Ceramide Ng, Adenosine, Sodium PCA, Ethylhexylglycerin, Panthenol, Allantoin, Tocopherol, Lactic Acid, Leuconostoc/Radish Root Ferment Filtrate, Phytic Acid, Cyclodextrin, Citric Acid, Sodium Hydroxide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyacrylate-13, Polyisobutene, Polysorbate 20, Maltodextrin, Sorbitan Isostearate, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.

It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.

The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.

The high linoleic acid content is particularly noteworthy for acne-prone skin.

Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.

One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).

This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.

On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.

Leuconostoc comes from lactic acid.

This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.

Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

Maltodextrin is a plant-derived carbohydrate made by breaking down starch (usually from corn, potato, or rice). In cosmetic formulas, it's a multitasking absorbent, emulsion stabilizer, and skin conditioner.

This ingredient is mostly used to stabilize emulsions and improve the powdery, non-greasy feel of products (like dry shampoos).

Safety-wise, this ingredient is pretty solid; it's even recognized as a food additive. Both animal and clinical studies found no adverse effects at the levels used in cosmetics.

Industry data shows this ingredient is used up to 45.7% in spray products and up to 33% in powder products.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

01
REFERENCE CARDS

Ingredients, lists & structured values

INGREDIENT LIST

Ingredients Explained

  • These ingredients are found in both products.
  • Ingredients higher up in an ingredient list are typically present in a larger amount.
  • Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  • Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  • However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  • Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  • In skincare formulas, citric acid can:
  • While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  • Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  • Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  • However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is u…
  • Curcuma Longa Root Extract comes from the rhizome (underground stem) of the turmeric plant.
  • While the official EU Cosing Database lists this ingredient as a fragrance, it actually does more than give products a scent.
  • This ingredient contains a group of yellow pigments called curcuminoids (mostly curcumin) that give it genuine antioxidant and anti-inflammatory activity in skin.
  • Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation.
  • One thing working in its favor is that curcumin barely penetrates; in lab skin-permeation testing, the curcuminoids mostly stayed in the outermost layer of skin. This is a good thing because its soothing and antioxidant activity is a surface-level job anyway.
  • At this time, industry data shows there's no single "correct" cosmetic percentage. It's used across a wide range depending on the product and varies from tiny fractions of a percent up to a few percent.
  • Allergy-wise, curcumin is a documented (but uncommon) contact allergen. It can also cross react with related plants, so anyone with a turmeric/ginger/cinnamon allergy or reactive skin should patch test first.
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PROVISION SHELF

Products & side-by-side records

Product

Skin 2.0 Vitamin C & Collagen

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Source: incidecoder.comOpen reference →