Hanskin Collagen Peptide Hydra Ampoule Versus The Potions Peptide Ampoule

Hanskin Collagen Peptide Hydra Ampoule Versus The Potions Peptide Ampoule

This anti-aging ampoule is formulated around Collagen Extract and Niacinamide to soften the look of wrinkles and hydrate skin.

This anti-aging ampoule is formulated around Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Collagen Extract

Glycerin

Butylene Glycol

Niacinamide

Betaine

Glycereth-26

Acetyl Hexapeptide-8

Copper Tripeptide-1

Oligopeptide-29

Oligopeptide-32

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-5

Octapeptide-7

Sh-Decapeptide-7

Sh-Octapeptide-4

Sh-Oligopeptide-9

Sh-Pentapeptide-19

Pentapeptide-18

Acetyl Tetrapeptide-5

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-22

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Hydrolyzed Elastin

Hydrolyzed Collagen

Sodium Hyaluronate

Sodium Acetylated Hyaluronate

Hydrolyzed Hyaluronic Acid

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Hyaluronic Acid

Potassium Hyaluronate

Hydrolyzed Extensin

Isostearic Acid

Sucrose Stearate

Phytosteryl/Octyldodecyl Lauroyl Glutamate

Octyldodecanol

Sodium Stearoyl Glutamate

1,2-Hexanediol

Ceramide NP

Squalane

Caprylic/Capric Glycerides

Xylitylglucoside

Anhydroxylitol

Xylitol

Water

Dextrin

Cyclodextrin

Pentylene Glycol

Cocos Nucifera Fruit Extract

Pinus Sylvestris Leaf Extract

Polyglyceryl-10 Laurate

Propanediol

Caprylyl Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Caprylic/Capric Triglyceride

Arginine

Chlorphenesin

Xanthan Gum

Adenosine

Sodium Polyacrylate

Disodium EDTA

Ethylhexylglycerin

Collagen Extract, Glycerin, Butylene Glycol, Niacinamide, Betaine, Glycereth-26, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Octapeptide-7, Sh-Decapeptide-7, Sh-Octapeptide-4, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Pentapeptide-18, Acetyl Tetrapeptide-5, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Hydrolyzed Elastin, Hydrolyzed Collagen, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Potassium Hyaluronate, Hydrolyzed Extensin, Isostearic Acid, Sucrose Stearate, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Octyldodecanol, Sodium Stearoyl Glutamate, 1,2-Hexanediol, Ceramide NP, Squalane, Caprylic/Capric Glycerides, Xylitylglucoside, Anhydroxylitol, Xylitol, Water, Dextrin, Cyclodextrin, Pentylene Glycol, Cocos Nucifera Fruit Extract, Pinus Sylvestris Leaf Extract, Polyglyceryl-10 Laurate, Propanediol, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylic/Capric Triglyceride, Arginine, Chlorphenesin, Xanthan Gum, Adenosine, Sodium Polyacrylate, Disodium EDTA, Ethylhexylglycerin

Dehydroxanthan Gum

Tranexamoyl Dipeptide-22

Hexapeptide-9

Tripeptide-29

Tripeptide-1

Nicotinoyl Dipeptide-22

Water, Butylene Glycol, Pentylene Glycol, Dehydroxanthan Gum, Tranexamoyl Dipeptide-22, Hexapeptide-9, Tripeptide-29, Tripeptide-1, Acetyl Hexapeptide-8, Nicotinoyl Dipeptide-22, Palmitoyl Pentapeptide-4, Copper Tripeptide-1

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.

As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.

A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.

The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.

The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.

Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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