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Nutrition guide

ISDIN Isdinceutics Hyaluronic Concentrate Versus Paula's Choice Pro-Collagen Multi-Peptide Booster

ISDIN Isdinceutics Hyaluronic Concentrate Versus Paula's Choice Pro-Collagen Multi-Peptide Booster This hydrating serum is formulated around Pseudoalteromonas Ferment Extract and Hydrolyzed Hyaluronic Acid to hydrate skin and soften the look of wrinkles. What'

ISDIN Isdinceutics Hyaluronic Concentrate Versus Paula's Choice Pro-Collagen Multi-Peptide Booster

This hydrating serum is formulated around Pseudoalteromonas Ferment Extract and Hydrolyzed Hyaluronic Acid to hydrate skin and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Propanediol

Glycerin

1,2-Hexanediol

Sodium Acrylates Copolymer

Dimethicone Crosspolymer

Butylene Glycol

Pseudoalteromonas Ferment Extract

Glycereth-26

Lecithin

Maltodextrin

Sodium Benzoate

Pentylene Glycol

Lens Esculenta Seed Extract

Parfum

Disodium EDTA

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate

Xanthan Gum

Citric Acid

Biosaccharide Gum-1

Carbomer

Polysorbate 20

Sodium Lactate

Sodium Salicylate

Salicylic Acid

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Water, Dimethicone, Propanediol, Glycerin, 1,2-Hexanediol, Sodium Acrylates Copolymer, Dimethicone Crosspolymer, Butylene Glycol, Pseudoalteromonas Ferment Extract, Glycereth-26, Lecithin, Maltodextrin, Sodium Benzoate, Pentylene Glycol, Lens Esculenta Seed Extract, Parfum, Disodium EDTA, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Xanthan Gum, Citric Acid, Biosaccharide Gum-1, Carbomer, Polysorbate 20, Sodium Lactate, Sodium Salicylate, Salicylic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

Hydrolyzed Yeast Extract

Pyrus Malus Fruit Extract

Ceramide AP

Glyceryl Glucoside

Palmitoyl Tetrapeptide-72 Amide

Sh-Polypeptide-121

Tridecapeptide-1

Polyglucuronic Acid

C9-12 Alkane

Ammonium Polyacryloyldimethyl Taurate

Polygonum Bistorta Root Extract

Bacillus Ferment

Sodium Phytate

Coco-Caprylate/Caprate

Hexylene Glycol

Cetyl Hydroxyethylcellulose

Ethylhexylglycerin

Caprylyl Glycol

Magnesium Chloride

Potassium Sorbate

Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, Ceramide AP, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tetrapeptide-72 Amide, Sh-Polypeptide-121, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate/Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

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REFERENCE CARDS

Ingredients, lists & structured values

INGREDIENT LIST

Ingredients Explained

  • These ingredients are found in both products.
  • Ingredients higher up in an ingredient list are typically present in a larger amount.
  • Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  • Topically, glycerin does several things at once:
  • Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  • Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  • This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  • Just know very high concentrations (>40%) can feel tacky in low humidity.
  • Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  • Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
  • So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
  • You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
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PROVISION SHELF

Products & side-by-side records