Collagen & Peptide NutritionNutrition and collagen guides

Nutrition guide

KAINE Green Calm Aqua Cream Versus KAINE Vegan Collagen Youth Cream

KAINE Green Calm Aqua Cream Versus KAINE Vegan Collagen Youth Cream This calming moisturizer is formulated around Panthenol and Camellia Sinensis Leaf Extract to calm redness and strengthen the skin barrier. This anti-aging moisturizer is formulated around Tre

KAINE Green Calm Aqua Cream Versus KAINE Vegan Collagen Youth Cream

This calming moisturizer is formulated around Panthenol and Camellia Sinensis Leaf Extract to calm redness and strengthen the skin barrier.

This anti-aging moisturizer is formulated around Tremella Fuciformis Extract and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Panthenol

1,2-Hexanediol

Cetyl Ethylhexanoate

Butylene Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Glycerin

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Tromethamine

Polyglyceryl-2 Stearate

Glyceryl Stearate

Stearyl Alcohol

Allantoin

Betaine

Squalane

Trehalose

Ethylhexylglycerin

Artemisia Capillaris Extract

Bambusa Arundinacea Juice

Camellia Sinensis Leaf Extract

Melia Azadirachta Leaf Extract

Hydrolyzed Gardenia Florida Extract

Hydrolyzed Malt Extract

Disodium EDTA

Hydrolyzed Viola Tricolor Extract

Sorbitan Isostearate

Ectoin

Melia Azadirachta Flower Extract

Hyaluronic Acid

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate

Theobroma Cacao Seed Extract

Dextrin

Water, Propanediol, Panthenol, 1,2-Hexanediol, Cetyl Ethylhexanoate, Butylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Tromethamine, Polyglyceryl-2 Stearate, Glyceryl Stearate, Stearyl Alcohol, Allantoin, Betaine, Squalane, Trehalose, Ethylhexylglycerin, Artemisia Capillaris Extract, Bambusa Arundinacea Juice, Camellia Sinensis Leaf Extract, Melia Azadirachta Leaf Extract, Hydrolyzed Gardenia Florida Extract, Hydrolyzed Malt Extract, Disodium EDTA, Hydrolyzed Viola Tricolor Extract, Sorbitan Isostearate, Ectoin, Melia Azadirachta Flower Extract, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Theobroma Cacao Seed Extract, Dextrin

Tremella Fuciformis Extract

Ethylhexyl Stearate

Hydrogenated Polyisobutene

Polyglyceryl-3 Distearate

Diisostearyl Malate

Caprylic/Capric Triglyceride

Niacinamide

Pentylene Glycol

Vinyldimethicone

Hydrogenated Coco-Glycerides

Theobroma Grandiflorum Seed Butter

Simmondsia Chinensis Seed Oil

Soluble Collagen

Boron Nitride

Glyceryl Stearate Citrate

Hydrogenated Lecithin

Palmitic Acid

Stearic Acid

Dipotassium Glycyrrhizate

Adenosine

Polyglyceryl-10 Stearate

Lauroyl Lysine

Sodium Phytate

Cholesterol

Beta-Glucan

Hydroxypropyltrimonium Hyaluronate

Tocopherol

Sodium Acetylated Hyaluronate

Hydrolyzed Sodium Hyaluronate

Sodium Hyaluronate Crosspolymer

Potassium Hyaluronate

Cetearyl Alcohol

Xanthan Gum

Carbomer

Tremella Fuciformis Extract, Glycerin, Water, Ethylhexyl Stearate, Hydrogenated Polyisobutene, Polyglyceryl-3 Distearate, Diisostearyl Malate, Caprylic/Capric Triglyceride, Butylene Glycol, Niacinamide, Pentylene Glycol, Vinyldimethicone, Hydrogenated Coco-Glycerides, 1,2-Hexanediol, Theobroma Grandiflorum Seed Butter, Simmondsia Chinensis Seed Oil, Sodium Hyaluronate, Soluble Collagen, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Glyceryl Stearate, Panthenol, Boron Nitride, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid, Stearic Acid, Allantoin, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Tromethamine, Adenosine, Polyglyceryl-10 Stearate, Lauroyl Lysine, Sodium Phytate, Sorbitan Isostearate, Cholesterol, Beta-Glucan, Hydroxypropyltrimonium Hyaluronate, Tocopherol, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate, Cetearyl Alcohol, Xanthan Gum, Carbomer

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.

It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.

Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.

Most formulations will combine all sizes to get the best of both worlds.

Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.

As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.

In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.

Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.

Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.

It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.

This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.

Concentration use ranges from 0.1-1.0% depending on the formula.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

01
REFERENCE CARDS

Ingredients, lists & structured values

INGREDIENT LIST

Ingredients Explained

  • These ingredients are found in both products.
  • Ingredients higher up in an ingredient list are typically present in a larger amount.
  • Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
  • The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol).
  • This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.
  • However, alcohol denat. is not all that bad.
  • Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
  • This also helps other ingredients become better absorbed upon application.
  • Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
  • Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
  • The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.
  • One thing to note: People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.
  • The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).
  • Also...
  • This ingredient has antimicrobial and solvent properties.
  • The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
  • Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.
  • This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.
Source trail · skinsort.com →
05
PROVISION SHELF

Products & side-by-side records