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Nutrition guide

MediCube Collagen Jelly Cream Versus Simply Vital Collagen, Retinol & Hyaluronic Acid Cream

MediCube Collagen Jelly Cream Versus Simply Vital Collagen, Retinol & Hyaluronic Acid Cream This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles. This anti-aging moisturizer is formulated around Retinol and Hyaluronic Aci

MediCube Collagen Jelly Cream Versus Simply Vital Collagen, Retinol & Hyaluronic Acid Cream

This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles.

This anti-aging moisturizer is formulated around Retinol and Hyaluronic Acid to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Dipropylene Glycol

Butylene Glycol

Methylpropanediol

Diethoxyethyl Succinate

Ethoxydiglycol

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Niacinamide

Trehalose

1,2-Hexanediol

Chlorella Vulgaris Extract

Collagen

Hydrolyzed Collagen

Cynanchum Atratum Extract

Althaea Rosea Flower Extract

Soluble Collagen

Allium Sativum Bulb Extract

Avena Sativa Kernel Extract

Bertholletia Excelsa Seed Extract

Brassica Oleracea Italica Extract

Camellia Sinensis Seed Extract

Salmon Egg Extract

Solanum Lycopersicum Fruit Extract

Spinacia Oleracea Leaf Extract

Vaccinium Angustifolium Fruit Extract

Wine Extract

Polyglyceryl-10 Isostearate

Tromethamine

Glucose

Polyglyceryl-10 Oleate

Ethylhexylglycerin

Fructooligosaccharides

Fructose

Adenosine

Sodium Phytate

Cyanocobalamin

Tocopherol

Pullulan

Glycerin

Hydroxypropyltrimonium Hyaluronate

Squalane

Soluble Proteoglycan

Hydrolyzed Elastin

Sodium DNA

Carbomer

Xanthan Gum

Parfum

Water, Propanediol, Dipropylene Glycol, Butylene Glycol, Methylpropanediol, Diethoxyethyl Succinate, Ethoxydiglycol, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Niacinamide, Trehalose, 1,2-Hexanediol, Chlorella Vulgaris Extract, Collagen, Hydrolyzed Collagen, Cynanchum Atratum Extract, Althaea Rosea Flower Extract, Soluble Collagen, Allium Sativum Bulb Extract, Avena Sativa Kernel Extract, Bertholletia Excelsa Seed Extract, Brassica Oleracea Italica Extract, Camellia Sinensis Seed Extract, Salmon Egg Extract, Solanum Lycopersicum Fruit Extract, Spinacia Oleracea Leaf Extract, Vaccinium Angustifolium Fruit Extract, Wine Extract, Polyglyceryl-10 Isostearate, Tromethamine, Glucose, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Adenosine, Sodium Phytate, Cyanocobalamin, Tocopherol, Pullulan, Glycerin, Hydroxypropyltrimonium Hyaluronate, Squalane, Soluble Proteoglycan, Hydrolyzed Elastin, Sodium DNA, Carbomer, Xanthan Gum, Parfum

Caprylic/Capric Triglyceride

Cocos Nucifera Oil

Simmondsia Chinensis Seed Oil

Aloe Barbadensis Sprout

Stearyl Alcohol

Stearic Acid

Isopropyl Myristate

Retinol

Hyaluronic Acid

Acrylates/Steareth-20 Methacrylate Copolymer

Phenoxyethanol

Caprylyl Glycol

Potassium Sorbate

Imidazolidinyl Urea

EDTA

Persea Gratissima Oil

Chamomilla Recutita Flower Extract

Tocopheryl Acetate

Water, Caprylic/Capric Triglyceride, Cocos Nucifera Oil, Simmondsia Chinensis Seed Oil, Aloe Barbadensis Sprout, Stearyl Alcohol, Stearic Acid, Isopropyl Myristate, Retinol, Hydrolyzed Collagen, Hyaluronic Acid, Acrylates/Steareth-20 Methacrylate Copolymer, Phenoxyethanol, Caprylyl Glycol, Potassium Sorbate, Imidazolidinyl Urea, EDTA, Carbomer, Persea Gratissima Oil, Chamomilla Recutita Flower Extract, Tocopheryl Acetate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.

In a formula, it works mainly as a skin-conditioning and moisturizing agent.

The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.

This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.

It's worth being realistic here:

Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).

However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.

Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).

Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.

If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.

The results are varied.

A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.

However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.

Further studies are needed at this time.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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SUPPLEMENTAL FIELD FILE

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