Collagen & Peptide NutritionNutrition and collagen guides

Nutrition guide

MediCube PDRN Pink Collagen Capsule Cream Versus Tatcha The Water Cream

MediCube PDRN Pink Collagen Capsule Cream Versus Tatcha The Water Cream This anti-aging moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles. This pore-care moisturizer is formulated around Saccharomyces/Rice Ferment Filtr

MediCube PDRN Pink Collagen Capsule Cream Versus Tatcha The Water Cream

This anti-aging moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles.

This pore-care moisturizer is formulated around Saccharomyces/Rice Ferment Filtrate and Camellia Sinensis Leaf Extract to refine the look of pores and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Niacinamide

Methylpropanediol

Propanediol

1,2-Hexanediol

Dipropylene Glycol

Caprylic/Capric Triglyceride

Glycereth-26

Arginine

Butylene Glycol

Ethylhexyl Palmitate

Cetearyl Alcohol

Carbomer

Cetearyl Olivate

Sorbitan Olivate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Simethicone

Eclipta Prostrata Extract

Ethylhexylglycerin

Adenosine

Polyacrylate-13

Sodium DNA

Disodium EDTA

Melia Azadirachta Leaf Extract

Polyisobutene

Hydrolyzed Sclerotium Gum

Glyceryl Stearate

Moringa Oleifera Seed Oil

Polysorbate 20

Sorbitan Isostearate

Sodium Hyaluronate

Glutathione

Octyldodecanol

Hydroxypropyltrimonium Hyaluronate

Salmon Egg Extract

Hydrogenated Lecithin

Ceramide NP

Cyanocobalamin

Thioctic Acid

Hydrolyzed Hyaluronic Acid

Hydrolyzed Collagen Extract

Sodium Acetylated Hyaluronate

Acetyl Hexapeptide-8

Copper Tripeptide-1

Hyaluronic Acid

Caprylyl Glycol

Palmitoyl Pentapeptide-4

Hydrolyzed Sodium Hyaluronate

Palmitoyl Hexapeptide-12

Sodium Hyaluronate Crosspolymer

Potassium Hyaluronate

Water, Glycerin, Niacinamide, Methylpropanediol, Propanediol, 1,2-Hexanediol, Dipropylene Glycol, Caprylic/Capric Triglyceride, Glycereth-26, Arginine, Butylene Glycol, Ethylhexyl Palmitate, Cetearyl Alcohol, Carbomer, Cetearyl Olivate, Sorbitan Olivate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Simethicone, Eclipta Prostrata Extract, Ethylhexylglycerin, Adenosine, Polyacrylate-13, Sodium DNA, Disodium EDTA, Melia Azadirachta Leaf Extract, Polyisobutene, Hydrolyzed Sclerotium Gum, Glyceryl Stearate, Moringa Oleifera Seed Oil, Polysorbate 20, Sorbitan Isostearate, Sodium Hyaluronate, Glutathione, Octyldodecanol, Hydroxypropyltrimonium Hyaluronate, Salmon Egg Extract, Hydrogenated Lecithin, Ceramide NP, Cyanocobalamin, Thioctic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Collagen Extract, Sodium Acetylated Hyaluronate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hyaluronic Acid, Caprylyl Glycol, Palmitoyl Pentapeptide-4, Hydrolyzed Sodium Hyaluronate, Palmitoyl Hexapeptide-12, Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate

Saccharomyces/Rice Ferment Filtrate

Dimethicone

Diglycerin

Diphenylsiloxy Phenyl Trimethicone

Camellia Sinensis Leaf Extract

Cladosiphon Okamuranus Extract

PEG-9 Polydimethylsiloxyethyl Dimethicone

Gold

Belamcanda Chinensis Root Extract

Rosa Multiflora Fruit Extract

Houttuynia Cordata Extract

Sophora Angustifolia Root Extract

Lecithin

Pistacia Lentiscus Gum

Sodium Chloride

Sodium Citrate

Mica

Tin Oxide

Dimethicone/PEG-10/15 Crosspolymer

Dimethicone/Phenyl Vinyl Dimethicone Crosspolymer

Tocopherol

Parfum

Alcohol

Phenoxyethanol

Limonene

Linalool

Citral

CI 77891

Water, Saccharomyces/Rice Ferment Filtrate, Dimethicone, Propanediol, Glycerin, Diglycerin, Diphenylsiloxy Phenyl Trimethicone, Camellia Sinensis Leaf Extract, Cladosiphon Okamuranus Extract, PEG-9 Polydimethylsiloxyethyl Dimethicone, Gold, Belamcanda Chinensis Root Extract, Rosa Multiflora Fruit Extract, Houttuynia Cordata Extract, Sophora Angustifolia Root Extract, Sodium Hyaluronate, Lecithin, Pistacia Lentiscus Gum, Sodium Chloride, Sodium Citrate, Mica, Tin Oxide, Dimethicone/PEG-10/15 Crosspolymer, Dimethicone/Phenyl Vinyl Dimethicone Crosspolymer, Tocopherol, Butylene Glycol, Ethylhexylglycerin, Dipropylene Glycol, Parfum, Alcohol, Phenoxyethanol, Limonene, Linalool, Citral, CI 77891

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

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REFERENCE CARDS

Ingredients, lists & structured values

INGREDIENT LIST

Ingredients Explained

  • These ingredients are found in both products.
  • Ingredients higher up in an ingredient list are typically present in a larger amount.
  • 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  • It is a:
  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives
  • Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
  • The way it works is fairly well mapped out:
  • Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their ow…
  • The clinical backing is pretty solid too.
  • A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
  • A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
  • On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
  • This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
  • Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
  • Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Source trail · skinsort.com →
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PROVISION SHELF

Products & side-by-side records

Product

Mediheal Collagen Capsule Patch

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Source: skinsort.comOpen reference →