Collagen & Peptide NutritionNutrition and collagen guides

Nutrition guide

Mizon Collagen Power Lifting Cream Versus Coxir Black Snail Collagen Cream

Mizon Collagen Power Lifting Cream Versus Coxir Black Snail Collagen Cream This anti-aging moisturizer is formulated around Houttuynia Cordata Extract and Copper Tripeptide-1 to soften the look of wrinkles. This moisturizer is formulated around Aloe Barbadensi

Mizon Collagen Power Lifting Cream Versus Coxir Black Snail Collagen Cream

This anti-aging moisturizer is formulated around Houttuynia Cordata Extract and Copper Tripeptide-1 to soften the look of wrinkles.

This moisturizer is formulated around Aloe Barbadensis Leaf Extract and Snail Secretion Filtrate to hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Hydrolyzed Collagen

Houttuynia Cordata Extract

Trehalose

Sorbitan Isostearate

Royal Jelly

Dextrin

Copper Tripeptide-1

Polyisobutene

Theobroma Cacao Extract

BHT

Glycerin

Beta-Glucan

Polyacrylate-13

Polysorbate 20

Phenoxyethanol

Cetearyl Dimethicone Crosspolymer

Cyclopentasiloxane

Propanediol

Iris Florentina Root Extract

Dimethicone

Adenosine

Coptis Chinensis Root Extract

Salvia Hispanica Seed Extract

Ethylhexylglycerin

Xanthan Gum

Bis-PEG-18 Methyl Ether Dimethyl Silane

Centella Asiatica Extract

Prunus Amygdalus Dulcis Seed Extract

Propolis Extract

Carbomer

Butylene Glycol

Hydrolyzed Royal Jelly Protein

1,2-Hexanediol

Cyclohexasiloxane

Disodium EDTA

Sodium Hyaluronate

Tromethamine

Water, Hydrolyzed Collagen, Houttuynia Cordata Extract, Trehalose, Sorbitan Isostearate, Royal Jelly, Dextrin, Copper Tripeptide-1, Polyisobutene, Theobroma Cacao Extract, BHT, Glycerin, Beta-Glucan, Polyacrylate-13, Polysorbate 20, Phenoxyethanol, Cetearyl Dimethicone Crosspolymer, Cyclopentasiloxane, Propanediol, Iris Florentina Root Extract, Dimethicone, Adenosine, Coptis Chinensis Root Extract, Salvia Hispanica Seed Extract, Ethylhexylglycerin, Xanthan Gum, Bis-PEG-18 Methyl Ether Dimethyl Silane, Centella Asiatica Extract, Prunus Amygdalus Dulcis Seed Extract, Propolis Extract, Carbomer, Butylene Glycol, Hydrolyzed Royal Jelly Protein, 1,2-Hexanediol, Cyclohexasiloxane, Disodium EDTA, Sodium Hyaluronate, Tromethamine

Aloe Barbadensis Leaf Extract

Dipropylene Glycol

Propylene Glycol

Caprylic/Capric Triglyceride

Olivoyl Hydrolyzed Wheat Protein

Cetearyl Alcohol

Glyceryl Oleate

Glyceryl Stearate

Glycereth-26

Orbignya Oleifera Seed Oil

Hydrogenated Polydecene

Hydroxyethylcellulose

Betaine

Triethanolamine

PEG-90m

Rosa Canina Fruit Oil

Panax Ginseng Root Extract

Camellia Sinensis Leaf Extract

Honey

Rosa Multiflora Fruit Extract

Gardenia Florida Fruit Extract

Scutellaria Baicalensis Root Extract

Ligustrum Japonicum Fruit Extract

Acanthopanax Senticosus Root Extract

Punica Granatum Fruit Extract

Carthamus Tinctorius Flower Extract

Glycine Soja Seed Extract

Sesamum Indicum Seed Extract

Oryza Sativa Extract

Panax Ginseng Berry Extract

Snail Secretion Filtrate

Leontopodium Alpinum Extract

Thymus Vulgaris Extract

Malva Sylvestris Flower Extract

Bambusa Vulgaris Leaf/Stem Extract

Parfum

Water, Aloe Barbadensis Leaf Extract, Butylene Glycol, Dipropylene Glycol, Propylene Glycol, Caprylic/Capric Triglyceride, Olivoyl Hydrolyzed Wheat Protein, Cetearyl Alcohol, Glyceryl Oleate, Glyceryl Stearate, Glycereth-26, Orbignya Oleifera Seed Oil, Hydrogenated Polydecene, Hydroxyethylcellulose, Betaine, Dimethicone, Triethanolamine, PEG-90m, Rosa Canina Fruit Oil, Panax Ginseng Root Extract, Camellia Sinensis Leaf Extract, Honey, Rosa Multiflora Fruit Extract, Gardenia Florida Fruit Extract, Scutellaria Baicalensis Root Extract, Ligustrum Japonicum Fruit Extract, Acanthopanax Senticosus Root Extract, Punica Granatum Fruit Extract, Carthamus Tinctorius Flower Extract, Glycine Soja Seed Extract, Sesamum Indicum Seed Extract, Oryza Sativa Extract, Theobroma Cacao Extract, Panax Ginseng Berry Extract, Snail Secretion Filtrate, Hydrolyzed Collagen, Copper Tripeptide-1, Adenosine, Leontopodium Alpinum Extract, Thymus Vulgaris Extract, Malva Sylvestris Flower Extract, Bambusa Vulgaris Leaf/Stem Extract, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Parfum

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.

In a formula, it works mainly as a skin-conditioning and moisturizing agent.

The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.

This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.

It's worth being realistic here:

Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).

However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.

Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).

Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.

If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.

The results are varied.

A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.

However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.

Further studies are needed at this time.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

This ingredient is extracted from the seeds of the cocoa tree.

Cacao seeds contain antioxidants known as polyphenols. These include flavonoids, procyanidins, and epicatechins.

Studies show these polyphenols help improve skin health.

The more famous ingredient from cocoa tree is cocoa butter.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

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PROVISION SHELF

Products & side-by-side records

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Endota Spa Collagen Power Boost Serum

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