Mizon Collagen Power Lifting Cream Versus Mary & May Idebenone Blackberry Intense Cream

Mizon Collagen Power Lifting Cream Versus Mary & May Idebenone Blackberry Intense Cream

This anti-aging moisturizer is formulated around Houttuynia Cordata Extract and Copper Tripeptide-1 to soften the look of wrinkles.

This barrier-repair moisturizer is formulated around Euterpe Oleracea Fruit Extract and Niacinamide to strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Hydrolyzed Collagen

Houttuynia Cordata Extract

Trehalose

Sorbitan Isostearate

Royal Jelly

Dextrin

Copper Tripeptide-1

Polyisobutene

Theobroma Cacao Extract

BHT

Glycerin

Beta-Glucan

Polyacrylate-13

Polysorbate 20

Phenoxyethanol

Cetearyl Dimethicone Crosspolymer

Cyclopentasiloxane

Propanediol

Iris Florentina Root Extract

Dimethicone

Adenosine

Coptis Chinensis Root Extract

Salvia Hispanica Seed Extract

Ethylhexylglycerin

Xanthan Gum

Bis-PEG-18 Methyl Ether Dimethyl Silane

Centella Asiatica Extract

Prunus Amygdalus Dulcis Seed Extract

Propolis Extract

Carbomer

Butylene Glycol

Hydrolyzed Royal Jelly Protein

1,2-Hexanediol

Cyclohexasiloxane

Disodium EDTA

Sodium Hyaluronate

Tromethamine

Water, Hydrolyzed Collagen, Houttuynia Cordata Extract, Trehalose, Sorbitan Isostearate, Royal Jelly, Dextrin, Copper Tripeptide-1, Polyisobutene, Theobroma Cacao Extract, BHT, Glycerin, Beta-Glucan, Polyacrylate-13, Polysorbate 20, Phenoxyethanol, Cetearyl Dimethicone Crosspolymer, Cyclopentasiloxane, Propanediol, Iris Florentina Root Extract, Dimethicone, Adenosine, Coptis Chinensis Root Extract, Salvia Hispanica Seed Extract, Ethylhexylglycerin, Xanthan Gum, Bis-PEG-18 Methyl Ether Dimethyl Silane, Centella Asiatica Extract, Prunus Amygdalus Dulcis Seed Extract, Propolis Extract, Carbomer, Butylene Glycol, Hydrolyzed Royal Jelly Protein, 1,2-Hexanediol, Cyclohexasiloxane, Disodium EDTA, Sodium Hyaluronate, Tromethamine

Rubus Fruticosus Fruit Extract

Euterpe Oleracea Fruit Extract

Vaccinium Angustifolium Fruit Extract

Caprylic/Capric Triglyceride

Niacinamide

Cetearyl Alcohol

Cetyl Ethylhexanoate

Isododecane

Ethylhexyl Palmitate

Cetearyl Olivate

Panthenol

Polyglyceryl-3 Methylglucose Distearate

Polyglyceryl-10 Laurate

Sorbitan Olivate

Sodium Polyacrylate

Hydrogenated Lecithin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Arginine

Hydrogenated Polydecene

Hydroxydecyl Ubiquinone

Pentylene Glycol

Trideceth-6

Glyceryl Acrylate/Acrylic Acid Copolymer

Caprylyl Glycol

Sodium Hyaluronate Crosspolymer

Stearic Acid

Hydrolyzed Hyaluronic Acid

Hyaluronic Acid

Hydrolyzed Sodium Hyaluronate

Ceramide NP

Ceramide Ns

Phytosphingosine

Cholesterol

Ceramide As

Ceramide AP

Ceramide EOP

Rubus Fruticosus Fruit Extract, Euterpe Oleracea Fruit Extract, Vaccinium Angustifolium Fruit Extract, Glycerin, Butylene Glycol, Water, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Niacinamide, Cetearyl Alcohol, Cetyl Ethylhexanoate, Isododecane, Ethylhexyl Palmitate, Cetearyl Olivate, Panthenol, Polyglyceryl-3 Methylglucose Distearate, Polyglyceryl-10 Laurate, Sorbitan Olivate, Sodium Polyacrylate, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Carbomer, Arginine, Hydrogenated Polydecene, Ethylhexylglycerin, Hydroxydecyl Ubiquinone, Adenosine, Pentylene Glycol, Trideceth-6, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Sodium Hyaluronate, Caprylyl Glycol, Sodium Hyaluronate Crosspolymer, Stearic Acid, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Ceramide NP, Ceramide Ns, Phytosphingosine, Cholesterol, Ceramide As, Ceramide AP, Ceramide EOP

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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