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Nutrition guide

Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free) Versus La Roche-Posay Toleriane Ultra Night Moisturizer

Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free) Versus La Roche-Posay Toleriane Ultra Night Moisturizer This anti-aging moisturizer is formulated around Niacinamide and Panthenol to soften the look of wrinkles and refine skin texture. This bar

Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free) Versus La Roche-Posay Toleriane Ultra Night Moisturizer

This anti-aging moisturizer is formulated around Niacinamide and Panthenol to soften the look of wrinkles and refine skin texture.

This barrier-repair night moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Niacinamide

Isohexadecane

Dimethicone

Isopropyl Isostearate

Stearyl Alcohol

Polyacrylamide

Panthenol

Palmitoyl Pentapeptide-4

Tremella Fuciformis Sporocarp Extract

Tapioca Starch

C13-14 Isoparaffin

Caprylyl Glycol

Dimethiconol

Laureth-7

Cetearyl Alcohol

Cetearyl Glucoside

Palmitic Acid

Stearic Acid

Cetyl Alcohol

Behenyl Alcohol

Disodium EDTA

PEG-100 Stearate

Titanium Dioxide

Polymethylsilsesquioxane

1,2-Hexanediol

Phenoxyethanol

Water, Glycerin, Niacinamide, Isohexadecane, Dimethicone, Isopropyl Isostearate, Stearyl Alcohol, Polyacrylamide, Panthenol, Palmitoyl Pentapeptide-4, Tremella Fuciformis Sporocarp Extract, Tapioca Starch, C13-14 Isoparaffin, Caprylyl Glycol, Dimethiconol, Laureth-7, Cetearyl Alcohol, Cetearyl Glucoside, Palmitic Acid, Stearic Acid, Cetyl Alcohol, Behenyl Alcohol, Disodium EDTA, PEG-100 Stearate, Titanium Dioxide, Polymethylsilsesquioxane, 1,2-Hexanediol, Phenoxyethanol

Squalane

Propanediol

Butylene Glycol

Butyrospermum Parkii Butter

Pentylene Glycol

Ammonium Polyacryloyldimethyl Taurate

Polysorbate 20

Tocopherol

Acetyl Dipeptide-1 Cetyl Ester

Allantoin

Toluene Sulfonic Acid

Xanthan Gum

Carnosine

Citric Acid

Aluminum Starch Octenylsuccinate

Glyceryl Acrylate/Acrylic Acid Copolymer

Water, Glycerin, Squalane, Propanediol, Butylene Glycol, Butyrospermum Parkii Butter, Pentylene Glycol, Niacinamide, Dimethicone, Ammonium Polyacryloyldimethyl Taurate, Polymethylsilsesquioxane, Polysorbate 20, Tocopherol, Acetyl Dipeptide-1 Cetyl Ester, Allantoin, Toluene Sulfonic Acid, Dimethiconol, Xanthan Gum, Carnosine, Disodium EDTA, Citric Acid, Aluminum Starch Octenylsuccinate, Glyceryl Acrylate/Acrylic Acid Copolymer

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Polymethylsilsesquioxane is a silicone used as a film forming agent.

When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.

Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.

If you have concerns about using this ingredient, we recommend speaking with a professional.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

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REFERENCE CARDS

Ingredients, lists & structured values

INGREDIENT LIST

Ingredients Explained

  • These ingredients are found in both products.
  • Ingredients higher up in an ingredient list are typically present in a larger amount.
  • C13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue.
  • This ingredient has been found to be non-sensitizing and safe for use in cosmetics.
  • Two things floating around online that cause fear-mongering:
  • There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effec…
  • The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredi…
  • One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.
  • Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  • What it does:
  • Dimethicone comes in different viscosities:
  • Depending on the viscosity, dimethicone has different properties.
  • Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
  • This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
  • Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
  • Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
  • This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
  • Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
Source trail · skinsort.com →
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PROVISION SHELF

Products & side-by-side records