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Nutrition guide

Pacifica Vegan Collagen Overnight Recovery Cream Versus Derma E Advanced Peptides And Collagen Moisturizer

Pacifica Vegan Collagen Overnight Recovery Cream Versus Derma E Advanced Peptides And Collagen Moisturizer This night moisturizer is formulated around Helianthus Annuus Seed Oil to hydrate skin. This anti-aging moisturizer is formulated around Palmitoyl Tripep

Pacifica Vegan Collagen Overnight Recovery Cream Versus Derma E Advanced Peptides And Collagen Moisturizer

This night moisturizer is formulated around Helianthus Annuus Seed Oil to hydrate skin.

This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-38 and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Helianthus Annuus Seed Oil

Glycerin

Sr-Hydrozoan Polypeptide-1

Cetyl Esters

Glyceryl Stearate

Cetyl Alcohol

Stearyl Alcohol

Stearic Acid

Tocopheryl Acetate

Diheptyl Succinate

Capryloyl Glycerin/Sebacic Acid Copolymer

Magnesium Ascorbyl Phosphate

Citrus Aurantium Dulcis Flower Extract

Jasminum Officinale Extract

Chamomilla Recutita Flower Extract

Arnica Montana Extract

Allantoin

Dipotassium Glycyrrhizate

Xanthan Gum

Phenoxyethanol

Ethylhexylglycerin

Parfum

Water, Helianthus Annuus Seed Oil, Glycerin, Sr-Hydrozoan Polypeptide-1, Cetyl Esters, Glyceryl Stearate, Cetyl Alcohol, Stearyl Alcohol, Stearic Acid, Tocopheryl Acetate, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Magnesium Ascorbyl Phosphate, Citrus Aurantium Dulcis Flower Extract, Jasminum Officinale Extract, Chamomilla Recutita Flower Extract, Arnica Montana Extract, Allantoin, Dipotassium Glycyrrhizate, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Parfum

Macadamia Ternifolia Seed Oil

Caprylic/Capric Triglyceride

Glyceryl Stearate Citrate

Dimethicone

Hydroxypropyl Cyclodextrin

Palmitoyl Tripeptide-38

Acetyl Hexapeptide-8

Panthenol

Pinus Pinaster Bark Extract

Glyceryl Stearate Se

Acacia Seyal Gum Extract

Ascorbyl Palmitate

Hamamelis Virginiana Bark/Leaf Extract

Aesculus Hippocastanum Seed Extract

Camellia Sinensis Leaf Extract

Chamomilla Recutita Flower

Simmondsia Chinensis Seed Oil

Potassium Sorbate

Sodium Hydroxide

Water, Glycerin, Macadamia Ternifolia Seed Oil, Caprylic/Capric Triglyceride, Stearic Acid, Cetyl Alcohol, Glyceryl Stearate Citrate, Dimethicone, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Acetyl Hexapeptide-8, Panthenol, Pinus Pinaster Bark Extract, Glyceryl Stearate Se, Acacia Seyal Gum Extract, Tocopheryl Acetate, Ascorbyl Palmitate, Hamamelis Virginiana Bark/Leaf Extract, Aesculus Hippocastanum Seed Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower, Simmondsia Chinensis Seed Oil, Allantoin, Xanthan Gum, Potassium Sorbate, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Parfum

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

SUPPLEMENTAL FIELD FILE

Notes to carry forward.

Source-derived references linked through this guide’s public topic markers.

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REFERENCE CARDS

Ingredients, lists & structured values

INGREDIENT LIST

Ingredients Explained

  • These ingredients are found in both products.
  • Ingredients higher up in an ingredient list are typically present in a larger amount.
  • Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  • Topically, glycerin does several things at once:
  • Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  • Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  • This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  • Just know very high concentrations (>40%) can feel tacky in low humidity.
  • Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  • Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
  • So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
  • You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
  • Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
  • On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
  • Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
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