S.NATURE Aqua Collagen Peptide Triple Gel Essence Versus Medik8 Liquid Peptides
S.NATURE Aqua Collagen Peptide Triple Gel Essence Versus Medik8 Liquid Peptides This hydrating essence is formulated around Acetyl Hexapeptide-8 and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles. This anti-aging serum is formulated around
S.NATURE Aqua Collagen Peptide Triple Gel Essence Versus Medik8 Liquid Peptides
This hydrating essence is formulated around Acetyl Hexapeptide-8 and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.
This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Butylene Glycol
Glycerin
Sorbitol
1,2-Hexanediol
Hydrolyzed Collagen
Acetyl Hexapeptide-8
Sodium Hyaluronate
Adenosine
Hydroxypropyltrimonium Hyaluronate
Sodium Acetylated Hyaluronate
Hydrolyzed Hyaluronic Acid
Hyaluronic Acid
Sodium Hyaluronate Crosspolymer
Hydrolyzed Sodium Hyaluronate
Potassium Hyaluronate
Allantoin
Betaine
Arginine
Centella Asiatica Extract
Polygonum Cuspidatum Root Extract
Scutellaria Baicalensis Root Extract
Camellia Sinensis Leaf Extract
Glycyrrhiza Glabra Root Extract
Chamomilla Recutita Flower Extract
Rosmarinus Officinalis Leaf Extract
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Hydroxyethylcellulose
Caprylyl Glycol
Water, Butylene Glycol, Glycerin, Sorbitol, 1,2-Hexanediol, Hydrolyzed Collagen, Acetyl Hexapeptide-8, Sodium Hyaluronate, Adenosine, Hydroxypropyltrimonium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Allantoin, Betaine, Arginine, Centella Asiatica Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Extract, Rosmarinus Officinalis Leaf Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxyethylcellulose, Caprylyl Glycol
Inulin
Panthenol
Alpha-Glucan Oligosaccharide
Carnosine
Carbomer
Polysorbate 20
Phenoxyethanol
Hydroxypropyl Cyclodextrin
Dunaliella Salina Extract
Ethylhexylglycerin
Citric Acid
Palmitoyl Tripeptide-5
Sodium Benzoate
Tetrapeptide-21
Pentapeptide-18
Palmitoyl Tripeptide-1
Pantolactone
Palmitoyl Tripeptide-38
Palmitoyl Tetrapeptide-7
Glyceryl Caprylate
Lactic Acid/Glycolic Acid Copolymer
Polyvinyl Alcohol
Phenylpropanol
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Potassium Sorbate
Xanthan Gum
Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!