Shiseido Tsubaki Premium Moist Conditioner Versus OGX Beauty Biotin & Collagen Conditioner

Shiseido Tsubaki Premium Moist Conditioner Versus OGX Beauty Biotin & Collagen Conditioner

What's inside

Key Ingredients

No key ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Isopentyldiol

Stearyl Alcohol

Behentrimonium Chloride

Glycerin

Dimethicone

Cetearyl Alcohol

Behenyl Alcohol

Aminopropyl Dimethicone

Hydrogenated Polyisobutene

Steartrimonium Chloride

Polysilicone-13

Camellia Seed Oil

Lactic Acid

Lysine Lauroyl Glutamate

Royal Jelly Extract

Glycine Max Seed Extract

Isopropyl Alcohol

Dipropylene Glycol

Isopropyl Myristate

PEG-2 Laurate

Salicylic Acid

Amodimethicone

PPG-2-Deceth-12

Methylserine

Disodium EDTA

Cetrimonium Chloride

Butylene Glycol

Tocopherol

Sodium Benzoate

Phenoxyethanol

Aroma

CI 17200

CI 15985

Water, Isopentyldiol, Stearyl Alcohol, Behentrimonium Chloride, Glycerin, Dimethicone, Cetearyl Alcohol, Behenyl Alcohol, Aminopropyl Dimethicone, Hydrogenated Polyisobutene, Steartrimonium Chloride, Polysilicone-13, Camellia Seed Oil, Lactic Acid, Lysine Lauroyl Glutamate, Royal Jelly Extract, Glycine Max Seed Extract, Isopropyl Alcohol, Dipropylene Glycol, Isopropyl Myristate, PEG-2 Laurate, Salicylic Acid, Amodimethicone, PPG-2-Deceth-12, Methylserine, Disodium EDTA, Cetrimonium Chloride, Butylene Glycol, Tocopherol, Sodium Benzoate, Phenoxyethanol, Aroma, CI 17200, CI 15985

Cetyl Alcohol

Biotin

Hydrolyzed Collagen

Hydrolyzed Wheat Protein

Ethyltrimonium Chloride Methacrylate/Hydrolyzed Wheat Protein Copolymer

PPG-3 Benzyl Ether Myristate

Polyquaternium-47

Steareth-20

Citric Acid

Sodium Hydroxide

Parfum

CI 60730

Water, Cetearyl Alcohol, Cetyl Alcohol, Behentrimonium Chloride, Biotin, Hydrolyzed Collagen, Hydrolyzed Wheat Protein, Ethyltrimonium Chloride Methacrylate/Hydrolyzed Wheat Protein Copolymer, Glycerin, PPG-3 Benzyl Ether Myristate, Dimethicone, Polyquaternium-47, Steareth-20, Disodium EDTA, Isopropyl Alcohol, Citric Acid, Sodium Hydroxide, Sodium Benzoate, Parfum, CI 60730, CI 17200

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is a preservative and often used for it's anti-static properties. You'll most likely see this ingredient in hair conditioners.

It does not cause irritation or sensitization in leave-on products at 1-5%.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

CI 17200 is a synthetic, water-soluble, reddish-pink dye. It is used purely as a cosmetic colorant.

In the US, the FDA permits this ingredient in cosmetics but it is not approved for use around the eyes while the EU allows this to be used in all cosmetic products.

The FDA requires batch-to-batch certification for this ingredient that is held to a pretty rigorous standard. That means the CI 17200 in your cosmetics has been tested and approved before it ever reaches you.

Contact allergy to cosmetic-grade dyes used at low concentrations are uncommon but has been documented before.

This ingredient also goes by the name D&C RED NO. 33.

CI 17200 has a comedogenic rating of 1 and an irritancy rating of 2 on a scale of 0-5. This is based on peer-reviewed research from the man who invented the comedogenic scale.

A 1 on the comedogenic scale is about as low as it gets without being a flat zero, and makes sense for CI 17200.

It's a water-soluble dye used at very small concentrations (typically 0.001-0.1%), so it dissolves into the water phase of a formula rather than sitting on your skin the way an oil or wax would.

The irritancy rating of 2 reflects that, like most synthetic dyes, there's a small possibility of mild irritation ( particularly for people with existing dye sensitivities).

For the vast majority of people, it's a non-issue at typical use levels.

It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.

Just so you know, the FDA ban on Red Dye No. 3 refers to CI 45430, not this ingredient. CI 45430 and CI 17200 are different chemical compounds with distinct safety and regulatory histories.

It's also worth noting that Red No. 3 (CI 45430) was already banned from cosmetics back in 1990, so the 2025 action just extended the ban to food and oral drugs. CI 17200 was never part of any of this.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Isopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.

This ingredient is an astringent alcohol. Astringent alcohols may also irritate skin as they high amounts may strip away your skin's natural oils.

Other types of astringent alcohols include:

According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.

Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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