Skin Aesthetics Advanced Brightening Facial Serum With Vitamin C & Collagen Versus 9wishes Mega Vitamin Ampule Serum

Skin Aesthetics Advanced Brightening Facial Serum With Vitamin C & Collagen Versus 9wishes Mega Vitamin Ampule Serum

This brightening serum is formulated around Niacinamide and Ascorbic Acid to brighten dull-looking skin and fade the look of dark spots.

This brightening serum is formulated around Niacinamide and Ascorbic Acid to brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

Dipropylene Glycol

Betaine

Niacinamide

Panthenol

Sodium Hyaluronate

Ascorbic Acid

Soluble Collagen

Aloe Barbadensis Leaf Extract

Camellia Sinensis Leaf Extract

Centella Asiatica Extract

Houttuynia Cordata Extract

Glyceryl Acrylate/Acrylic Acid Copolymer

Carbomer

Hydroxyethylcellulose

Ammonium Polyacryloyldimethyl Taurate

PEG-60 Hydrogenated Castor Oil

Arginine

1,2-Hexanediol

Ethylhexylglycerin

Hydroxyacetophenone

Parfum

Water, Glycerin, Dipropylene Glycol, Betaine, Niacinamide, Panthenol, Sodium Hyaluronate, Ascorbic Acid, Soluble Collagen, Aloe Barbadensis Leaf Extract, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Houttuynia Cordata Extract, Glyceryl Acrylate/Acrylic Acid Copolymer, Carbomer, Hydroxyethylcellulose, Ammonium Polyacryloyldimethyl Taurate, PEG-60 Hydrogenated Castor Oil, Arginine, 1,2-Hexanediol, Ethylhexylglycerin, Hydroxyacetophenone, Parfum

Pyrus Malus Fruit Water 50%

Sciadopitys Verticillata Root Extract 25%

Butylene Glycol

Honey Extract

Hippophae Rhamnoides Fruit Extract

Biota Orientalis Leaf Extract

Polyglyceryl-4 Caprate

Caprylyl Glycol

Glycosyl Trehalose

Beta-Glucan

Zanthoxylum Schinifolium Leaf Extract

Hydrogenated Starch Hydrolysate

Polygonum Cuspidatum Root Extract

Dipotassium Glycyrrhizate

Tocopheryl Acetate

Pentylene Glycol

Aspalathus Linearis Extract

Glycyrrhiza Glabra Root Extract

Commiphora Myrrha Resin Extract

Perilla Frutescens Leaf Extract

Yucca Schidigera Root Extract

Pyrus Malus Fruit Water 50%, Sciadopitys Verticillata Root Extract 25%, Glycerin, Dipropylene Glycol, Butylene Glycol, Sodium Hyaluronate, Water, Honey Extract, Hippophae Rhamnoides Fruit Extract, Biota Orientalis Leaf Extract, 1,2-Hexanediol, Betaine, Polyglyceryl-4 Caprate, Caprylyl Glycol, Glycosyl Trehalose, Beta-Glucan, Zanthoxylum Schinifolium Leaf Extract, Hydrogenated Starch Hydrolysate, Carbomer, Arginine, Polygonum Cuspidatum Root Extract, Hydroxyethylcellulose, Niacinamide, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Ascorbic Acid, Tocopheryl Acetate, Pentylene Glycol, Aspalathus Linearis Extract, Glycyrrhiza Glabra Root Extract, Commiphora Myrrha Resin Extract, Perilla Frutescens Leaf Extract, Yucca Schidigera Root Extract

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.

Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:

Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.

One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.

While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.

The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.

Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.

Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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